DbcAMP regulates adipogenesis in sheep inguinal preadipocytes

IL-17 Regulates Adipogenesis, Glucose

Prieurianin Causes Weight Loss in Diet-Induced Obese Mice and Inhibits Adipogenesis in Cultured Preadipocytes.

The global increase in the incidence of obesity has emerged as one of the most serious public health risks in recent years. Despite the enormity of the obesity pandemic, there are currently only two FDA-approved therapies for its treatment and these drugs exhibit modest efficacy and have limiting side effects. Prieurianin is a plant limonoid product that deters feeding in insect larvae. We inve...

Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes.

Fat distribution varies among individuals with similar body fat content. Innate differences in adipose cell characteristics may contribute because lipid accumulation and lipogenic enzyme activities vary among preadipocytes cultured from different fat depots. We determined expression of the adipogenic transcription factors peroxisome proliferator activated receptor-gamma (PPAR-gamma) and CCAAT/e...

Effects of Cnidium Officinale (Makino) and Ulmus Pumila (Linne.) Extracts on Adipogenesis in 3T3-L1 Preadipocytes

Certain natural therapeutic plant extracts and bioactive compounds, which are commonly used as components of East Asian medicine, have the tendency to promote adipogenesis through preadipocyte proliferation and differentiation. In this study, methanol extracts Cnidium officinale Makino and Ulmus pumila Linne were screened for their ability to induce preadipocyte proliferation and differentiatio...

Glucocorticoid-induced androgen inactivation by aldo-keto reductase 1C2 promotes adipogenesis in human preadipocytes.

Adipogenesis and lipid storage in human adipose tissue are inhibited by androgens such as DHT. Inactivation of DHT to 3α-diol is stimulated by glucocorticoids in human preadipocytes. We sought to characterize glucocorticoid-induced androgen inactivation in human preadipocytes and to establish its role in the antiadipogenic action of DHT. Subcutaneous and omental primary preadipocyte cultures we...